Pellagra - A Disease Caused by Vitamin B3 and/or Tryptophan Deficiency

Providing the body with all essential nutrients is vital to support health and prevent disease. Research has revealed that insufficient intake of nutrients leads to subclinical deterioration of function with detrimental effects on health and wellness. While nutrients deficiency results in a variety of serious diseases that can be life threatening.

Pellagra is a disease caused by Niacin and/or tryptophan deficiency, and often also involving insufficient intake of other B complex vitamins. The lack of these essential nutrients has repercussions on nervous system, skin and gastrointestinal tract. The typical symptoms of pellagra include dementia, diarrhoea and dermatitis. Other symptoms of this disease include weakness, loss of appetite, abdominal pain and inflamed mucous membranes.

Pellagra can be cured by increasing the intake of niacin, tryptophan, and other B complex vitamins. Moreover, it is extremely important to consider that the optimal intake of nutrients can prevent the development of pellagra.

In order to optimise the intake of essential nutrients, it is critical to consider that due to soil impoverishment, the food contains a reduced amount of micronutrients, compared with few decades ago. Additionally, the amount of essential micronutrients in processed, junk food is much less.

There is evidence to suggest that the widespread consumption of calories-rich, micronutrients-poor junk food, is a major factor for the dramatic increase in morbidity observed worldwide.

Also, it should be considered that pesticides and other toxic substances present in food nowadays, are a major cause of gastrointestinal diseases, which impair the body’s ability to absorb micronutrients.

Therefore, the use of dietary supplements can play a central role for ensuring optimal intake of micronutrients, and thus prevent diseases such as pellagra, promote normal physiological functions and support health.

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